WebNov 1, 2024 · BNT211 is currently being investigated as a monotherapy and in combination with a CLDN6-encoding mRNA-based vaccine (CARVac) in a first-in-human Phase 1/2 clinical trial ( NCT04503278) to... WebNext-generation CAR-T therapy BNT211 We additionally activate the CAR-T cells with our mRNA technology which boosts their power to target cancer cells BNT211 is a product candidate that may help the body’s natural defense by recognizing and destroying cancer cells that have a certain protein on their surface. mRNA vaccine (CARVac) CAR-T cell ...
CLDN6-Targeting CAR T-Cell Therapy Produces Acceptable …
Web958 BNT211: a phase I/II trial to evaluate safety and efficacy of CLDN6 CAR-T cells and vaccine-mediated in vivo expansion in patients with CLDN6-positive advanced solid tumors Mackensen, Andreas ; Koenecke, Christian ; Haanen, John ; Alsdorf, Winfried ; Desuki, Alexander; et al. Journal for Immunotherapy of Cancer; London Vol. 9, Iss. WebJan 3, 2024 · For instance, BNT211 is a combination of a CAR-T cell therapy targeting the antigen Claudin-6 (CLDN6) with a CLDN6-encoding CAR-T cell amplifying RNA vaccine (CARVac). Combining its technologies ... iron eating cockroach movie
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WebApr 11, 2024 · BNT211 is a potential first-in-class therapeutic approach which comprises two drug products, an autologous CAR-T cell therapy targeting the oncofetal antigen Claudin-6 (CLDN6) and a CLDN6-encoding ... WebAbstract CT002: BNT211: A Phase I trial to evaluate safety and efficacy of CLDN6 CAR-T cells and CARVac-mediated in vivo expansion in patients with CLDN6-positive advanced solid tumors. iron edge coupon code