Phospho eif4b

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August undefined, 2024

WebRecombinant Recombinant Anti-eIF4B (phospho S406) antibody [EPR7683] (ab134138) Datasheet SDS Submit a review Submit a question References (2) Key features and details Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply Rabbit monoclonal [EPR7683] to eIF4B (phospho S406) Suitable for: … WebThe eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP.

SignalSilence® eIF4B siRNA Cell Signaling Technology

WebAug 17, 2014 · Phospho-proteomics identified the mTOR pathway to be of interest in EGFR inhibitor resistance. In our studies, combining gefitinib and temsirolimus decreased cell growth and survival in a synergistic manner. Our data identified eIF4B, as a potentially key fragile point in EGFR and mTOR inhibitor synergy. WebeIF4B (eukaryotic translation initiation factor 4B), an RNA binding protein, is essential for the binding of mRNA to the 43S pre-initiation complex, which consists of the 40S ribosomal … grahams plumbers merchants bradford

Phospho-EIF4B (Ser497) Polyclonal Antibody - Thermo Fisher Scientific

WebJun 8, 2006 · eIF4B Ser422 phosphorylation persists in cells lacking S6K1 and S6K2 To further corroborate the existence of an eIF4B kinase that is distinct from S6K in cells … WebJan 9, 2012 · The lower lane shows tubular cell expression of actin under similar conditions. A bar diagram shows cumulative data of four sets of experiments in the right panel. B. Representative gels (in duplicate) showing tubular cell expression of phospho-eIF4B under control (vector) and HIV infection states (upper lane). WebEIF4B is one of the mammalian eukaryotic initiation factors (eIF) that are required for the ATP-dependent binding of mRNA to the 40 S ribosomal subunit, and the other eIF proteins … china hydraulic breaker bush

Human Phospho-eIF4B (S422) Antibody MAB3800: R&D …

Phospho-eIF4B (Ser406) Antibody Cell Signaling …

WebPhospho-EIF4B (Ser406) EIF4B (Eukaryotic Translation Initiation Factor 4B) is a Protein Coding gene. Among its related pathways are Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S and Viral mRNA Translation. Gene Ontology (GO) annotations related to this gene include nucleic acid binding ... Web人载脂蛋白A4(Apo-A4)ELISA试剂盒；英文名称： Human Apo-A4 ELISA Kit ；实验名称：人载脂蛋白A4(Apo-A4)ELISA试剂盒；实验别名：人载脂蛋白A4(Apo-A4)ELISA试剂盒 48T/96T ；规格： 48T/96T 报价人载脂蛋白A4(Apo-A4)ELISA试剂盒实验目的：本试剂盒仅供研究使用，用于用于测定血清、血浆及相关液体样本中待测物质 ... china hydraulic ball valveWebThe eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. china hydraulic bending press company

"WebPhospho-eIF4E (Ser209) Antibody detects endogenous levels of eIF4E only when phosphorylated at serine 209. Species Reactivity: Human, Mouse, Rat, Monkey Source / Purification Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser209 of human eIF4E. " - Phospho eif4b

Phospho eif4b

WebNov 18, 2016 · The activity of eIF4B is modulated by phosphorylation, which is mediated by two major signaling pathways, the MEK1/2-ERK1/2-RSK pathway and the PI3K-Akt-mTORC1-S6K pathway [8], [9], [11], [12]. Overexpression or depletion of eIF4B affects cell survival and proliferation [13], [14]. WebPhospho-eIF4B (Ser406) Antibody detects endogenous levels of eIF4B protein only when phosphorylated at Ser406. Species Reactivity: Human, Mouse. Species predicted to react …

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WebPhospho-EIF4B-S422 Rabbit pAb (AP0278) Datasheet SDS Tested applications: WB IHC Reactivity: Human, Mouse Western blot analysis of extracts from HeLa cells using … WebWestern blot analysis of extracts from HeLa cells, untransfected or transfected with SignalSilence ® eIF4B siRNA #6416, using Phospho-eIF4B (Ser422) Antibody (upper) or eIF4B Antibody #3592 (lower). 48 hours following transfection, cells were treated with Rapamycin (50 nM) and U0126 (10 uM) as indicated.

Web上海谷研实业有限公司主要从事免疫学、分子生物学和常规生化试剂的销售,主营产品:生化试剂、试剂盒、elisa试剂盒、抗体、重组蛋白、生化检测试剂盒、分光光度法检测试剂盒、荧光定量pcr检测试剂盒、细胞株、原代细胞、细胞培养基、标准溶液产品。 WebProduct Details Target Information The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP.

WebApr 6, 2024 · The protein expression of mTOR, phospho-mTOR, p70 S6 kinase (p70 S6K), phospho-p70 S6K, eIF4B, phospho-eIF4B, eIF4G, 4E-BP1, phospho-4E-BP1, eIF4E, phospho-eIF4E, and Rpb1 in the liver was assessed using western blotting. Actin was used as the loading control. (Specific antibody information is provided in the Supplementary Materials.) WebSep 5, 2024 · eIF4B phosphorylation patterns in hippocampal neurons and cortical astrocytes. ( A) Western blot analysis of total cell extracts from neurons or astrocytes …

WebJan 25, 2024 · We hypothesised that the effect of SLC25A11 knockdown on inhibiting protein translation was mediated by the inactivation of translational elongation factors such as eIF4B through the depletion of the ATP supply, which resulted in a critical reduction of p-eIF4B dependent synthesis of proteins including c-Myc in cancer cells (Fig. 4 b). china hydraulic bankable valve manufacturersWebEIF4B is one of the mammalian eukaryotic initiation factors (eIF) that are required for the ATP-dependent binding of mRNA to the 40 S ribosomal subunit, and the other eIF proteins are EIF4A, EIF4F. eIF4B is involved in translation of numerous proliferative or anti-apoptotic mRNAs with highly structured 5'UTR and subsequently affect cell growth … grahams plumbers merchant bracknellWebThe eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and … china hydraulic adapters fittings quotesWebPhospho-EIF4B-S422 Rabbit pAb (AP0775) Datasheet SDS Tested applications: WB Reactivity: Human Western blot analysis of extracts of HeLa cells, using Phospho-EIF4B-S422 antibody (AP0775) at 1:2000 dilution. HeLa cells were treated by EGF (100ng/mL) for 30 minutes after serum-starvation overnight. china hydraulic bending press manufacturersWeb酶联生物为您提供大鼠热休克蛋白β6(hspβ6)检测试剂盒的参数及2024年最新报价，厂家专业的大鼠热休克蛋白β6(hspβ6)检测试剂盒售后服务团队，是您值得信赖的合作伙伴 grahams plumbers merchants branchesWebJan 25, 2024 · We hypothesised that the effect of SLC25A11 knockdown on inhibiting protein translation was mediated by the inactivation of translational elongation factors … china hybrid latex mattressWebAug 4, 2024 · Phosphorylated eIF4B levels are normalized against total eIF4B, then for loading (Tubulin) and shown as fold change over control (untreated neurons). Data are … china hut on clark